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CAS 13647-35-3 Anti Estrogen Steroids Trilostane For Cushing'S Syndrome Cure

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CAS 13647-35-3 Anti Estrogen Steroids Trilostane For Cushing'S Syndrome Cure

Brand Name : Jusheng Brand
Model Number : 13647-35-3
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10g
Price : Discount is possible if your order is big enough
Payment Terms : T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability : 50KG / Month
Delivery Time : within 2 working days
Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
CAS : 13647-35-3
Alias : Trilostane
Apparence : Almost White Crystalline Powder
Purity : 99.5%
Stock : Enough Stock
Grade : Pharma Grade
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Trilostane CAS 13647-35-3 Anti Estrogen Steroids Treatment of Cushing's Syndrome

Quick detail


Trilostane
CAS No.:13647-35-3
Synonyms:Trilostane; Vetoryl; Modrastane; Desopan; modrenal; Modrefen;
Formula:C20H27NO3
Exact Mass:329.19900
Molecular Weight:329.43300
PSA:76.78000
LogP:3.46688
Properties
Appearance:tan crystals
Density:1.25g/cm3
Melting Point:264ºC
Boiling Point:516.5ºC at 760 mmHg
Flash Point:266.1ºC
Refractive Index:1.61
Vapor Pressure:5.39E-12mmHg at 25°C


Trilostane Introduction


Trilostane is an enzyme inhibiting medication. Its principal use is in the treatment of canine Cushing’s disease. In some cases, trilostane may also be an appropriate treatment for horses, cats and other conditions.

Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. These are both disorders where excess amounts of corticosteroid hormones are produced in the body. Corticosteroids are essential for the body to make use of carbohydrates, fats and proteins and for a normal response to stress.

Trilostane can also be useful in the treatment of breast cancer that has relapsed in women who have gone through menopause.

Trilostane Uses in dogs


It is also the first drug approved to treat both pituitary-and adrenal-dependent Cushing's in dogs.

1.It has kidney or liver disease.
2.takes certain medications used to treat heart disease.
3.pregnant.
4.taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
5.had an allergic reaction to this or any other medicine.


Trilostane — Drug Interactions and Potential Side Effects


Potential side effects include vomiting, reduced appetite, weight loss, diarrhea and tiredness. Rare instances of death have been reported. As each patient reacts differently to trilostane, arriving at the appropriate dosage is crucial in preventing instances of overdose and achieving the best possible outcome.

Trilostane COA


TestsSpecificationsResults
IdentificationPositiveConfirm
Melting point257°C to 270°C261°C -266°C
AppearanceWhite to pale white solidWhite solid
Heavy metalsNo more than 20ppm10ppm
Loss on dryingNot more than 0.5%0.18%
Residue on IgnitionNot more than 0.1%0.02%
Solubility

soluble in dimethyl sulfoxide
soluble in pyridine
slightly soluble in ethanol
slightly soluble in water

Conforms
Conforms
Conforms
Conforms

Assay (microbial)Not less than 99.0%99.5%
Specific Rotation+137-139°137.0°
Related impuritiesnot more than 1.0%0.35%
HPLC puritynot less than 99.0%99.6%
Solvent ResiduesEthanol<5000ppm1000ppm
ConclusionComply with In-house standard.
StorageStore protected from light and moisture























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CAS 13647-35-3 Anti Estrogen Steroids Trilostane For Cushing'S Syndrome Cure Images

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