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Pharmaceutical Anti Estrogen Steroids Powder Fluconazole CAS 86386-73-4

Pharmaceutical Anti Estrogen Steroids Powder Fluconazole CAS 86386-73-4

Brand Name : Jusheng Brand
Model Number : 86386-73-4
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10g
Price : Discount is possible if your order is big enough
Payment Terms : T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability : 50KG / Month
Delivery Time : within 2 working days
Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
CAS : 86386-73-4
MF : C13H12F2N6O
Apparence : white to light yellow crystal powder
Purity : 99%
Usage : Anti Inflammatory , Anti Estrogen
Stock : Enough Stock
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Pharmaceutical Powder Anti Inflammatory Anti Estrogen Fluconazole CAS 86386-73-4

Quick detail

CAS No.:86386-73-4
Molecular Weight:306.27
Synonyms:Flucostat;Fluconazolum [Latin]; Biozolene; FLU;Zemyc; Forcan;FCZ; Diflucan; Flusol; Flukezol;Pritenzol;2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol;Biocanol;Fluzone;Cryptal;UK 49858;Syscan;Alflucoz;1H-1,2,4-Triazole-1-ethanol, R-(2,4-difluorophenyl)- R-(1H-1,2,4-triazol-1-ylmethyl)-;FLZ;Diflucan (TN);Flucazol; FLC;Canzol;Oxifugol;Fluconazole (JAN/USAN);Fungata;Mutum;FLCZ;Baten;alpha-(2,4-Difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol; Fluconazol [Spanish];Triflucan;Afungil;Zonal;Elazor;
Density:1.49 g/cm3
Melting Point:138-140 ºC
Boiling Point:579.8 ºC at 760 mmHg
Flash Point:304.4 ºC
Solubility:DMSO: 5 mg/mL
Appearance:white or off white crystalline powder

Fluconazole Description

Fluconazole is a novel kind triazole drug of anti-fungal infection which was first successfully developed by the American Pfizer with broad-spectrum anti-fungal effect. It belongs to a kind of systemic anti-fungal products and has high selectivity on the inhibitory effect of the fungal cytochrome P450-dependent enzyme. It is also a kind of potent and specific inhibitor for the fungi alcohol synthesis. Clinically it is mainly used for the treatment of vaginal candidiasis, thrush, atrophic oral candidiasis, fungal meningitis, pulmonary fungal infections, abdominal infections, urinary tract infections and skin fungi infection.

Uses of Furosemide

1, systemic candidiasis:including candidemia, disseminated candidiasis and other forms of invasive Candida infections such as the peritoneum, endocardium, lungs and urinary tract infections. It can also be applied to patients of malignant tumors, special-care patients, patients who received radiotherapy, chemotherapy or immunosuppressive therapy as well as patients who are susceptible to other factors such as infection of Candida. It can also be used for prevention of the occurrence of candida infection for bone marrow transplant patients upon receiving cytotoxic drugs treatment or radiation treatment.
2, cryptococcosis:including cryptococcal meningitis and the cryptococcal infection in other parts (such as lung, skin). It can be applied to the patient of normal immune function, AIDS patients as well as patient of suppressed immune function due to organ transplant and other reasons. AIDS patients can administer this kind of drug for maintenance therapy and prevention of the relapse of cryptococcal disease.
3, mucosal candidiasis:including oropharyngeal, esophageal, non-invasive bronchial mucosal candidiasis, pulmonary candidiasis, Candida urine disease, mucocutaneous and chronic atrophic oral candidiasis. It can be applied to patients of both normal immune function and with impaired immune function.

5, it can be used for the treatment of acute or recurrent vaginal candidiasis.

6, for leukemia patients or patients of other malignant tumor who is susceptible to fungal infection upon undergoing chemotherapy or radiotherapy can apply it as means of preventive treatment.
7, it can be used for the treatment coccidioidomycosis.
8, it can be used for treatment of fungal skin disease including fungal skin infections such as body ringworm, tinea pedis, tinea versicolor, tinea capitis, onychomycosis and nail ringworm.

9, fluconazole can also be used for the treatment of skin chromomycosis.
In August 2002, the voriconazole (Pfizer) which enters in the United States is the further structural modified derivative of fluconazole with its antibacterial activity against pathogenic yeast being higher than fluconazole. Some case reports have demonstrated that the drug can successfully cure some rare fungal disease.

Fluconazole Side Effects

1. Common Side Effects of Fluconazole

  • Headache is the most common side effect of taking fluconazole. Other side effects include: nausea, diarrhea, vomiting, rash, and stomach pain.
  • Serious Side Effects of Fluconazole
  • Changes in heart rhythm or electrical activity in the heart
  • Liver failure and inflammation, including an increase in liver enzyme levels and yellowing of the skin, nails, and whites of the eyes (jaundice)
  • Swelling of the lips, mouth, and tongue (angioedema)
  • A drop in white blood cell count or platelet count
  • Difficulty breathing

2. Seizures

  • High triglycerides, low potassium levels in the blood
  • Severe and potentially life-threatening skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis (TENs)
  • Rare Side Effects of Fluconazole
  • Fluconazole may cause some unpredictable side effects, including baldness and dizziness.

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