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Anti Aging Beta Nicotinamide

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Hubei Jusheng Technology Co., Ltd.
City: Wuhan
Province/State: Hubei
Country/Region: China
Contact Person:Miss Linda

Anti Aging Beta Nicotinamide

Brand Name : Jusheng Brand
Model Number : 1094-61-7
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10grams
Price : Discount is possible if your order is big enough
Payment Terms : T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability : 1000kg/month
Delivery Time : within 2 working days
Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
β-NMN CAS : 1094-61-7
β-NMN Alias : Beta-Nicotinamide Mononucleotide, 1094-61-7, Beta-NM ,β-NMN
β-NMN Apparence : Almost White Crystalline Powder
β-NMN Purity : 99%
Email : linda@hubeijusheng.com
Skype : live:linda_8965
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Anti-aging Raw Materials Beta-Nicotinamide Mononucleotide 1094-61-7 Beta-NM β-NMN


Quick detail


Product NameBeta-Nicotinamide Mononucleotide
Synonyms

BETA-NMN;Beta-Nicotinamide Mononucleotide;Beta-Nicotinamide Ribose Monophosphate; Nicotinamide-1-Ium-1-Beta-d-Ribofuranoside 5'-Phosphate; Nicotinamide Ribotide; Nicotinamide Mononucleotide; 3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyridinium

CAS1094-61-7
EINECS214-136-5
MFC11H15N2O8P
MW334.22
Chemical PropertiesWhite to yellowish lyophilized powder
Assay97%min
StandardEnterprise Standard
UsageCosmetic raw material. A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice . It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

β-NMN​​ Description


The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca2+ signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.


NMNAT1 is the most widely expressed of three orthologous genes with nicotinamide-nucleotide adenylyltransferase (NMNAT) activity. Genetically engineered mice lacking NMNAT1 die during early embryogenesis, indicating a critical role of this gene in organismal viability.[citation needed] In contrast, mice lacking NMNAT2, which is expressed predominantly in neural tissues, complete development but die shortly after birth. However, NMNAT1 is dispensable for cell viability, as homozygous deletion of this gene occurs in glioblastoma tumors and cell lines. NMNAT enzymatic activity is probably essential at the cellular level, as complete ablation of NMNAT activity in model organisms leads to cellular inviability.


β-NMN Usage:

A product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice . It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.

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