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Cancer Cure 10 Deacetylbaccatin

Cancer Cure 10 Deacetylbaccatin

Brand Name : Jusheng Brand
Model Number : 32981-86-5
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10grams
Price : Discount is possible if your order is big enough
Payment Terms : T/T in advance, Money Gram, Western Union, Bank Transfer.
Supply Ability : 1000kg/month
Delivery Time : within 2 working days
Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
CAS : 32981-86-5
Apparence : White Powder
Purity : 99%
Other name : 10-Deacetylbaccatin III, 10-DAB-III
Usage : Cancer Cure
Grade : Pharma Grade
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Miscellaneous Natural Cancer Cure Drugs 10-Deacetylbaccatin III CAS 32981-86-5


Quick detail


Name:10-Deacetylbaccatin
CAS No.:32981-86-5
Formula:C29H36O10
Molecular Weight:544.60
Synonyms:DESACETYLBACCATINE;BACCATIN III, 10-DEACETYL-;10-O-DEACETYLBACCATIN III;10-DAB-III;10-DEACETYLBACCATIN;12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one;10-deacetylbaccatin11;10-deacetylbaccatiniii(extaxusbaccata)
Density:1.41 g/cm3
Melting Point:231-236 °C
Boiling Point:716.8 °C at 760 mmHg
Flash Point:233.5 °C
Solubility:Insoluble in water
Appearance:white solid

Hazard CodesT
Risk Statements23/24/25
Safety Statements45-38-36/37/39-28A
RIDADR1544
WGK Germany3
HazardClass6.1(b)
PackingGroupIII

10-Deacetylbaccatin III Description:


110-Deacetylbaccatin III is a natural organic compound isolated from the bark of the Pacific yew tree (Taxus brevifolia) and related species.
210-Deacetylbaccatin III is used as a chemical intermediate in the preparation of the anti-cancer drug paclitaxel.
310-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species.
410-Deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere)
510-deacetylbaccatin III 10-O-acetyltransferase converts 10-deacetylbaccatin to baccatin III:

10-Deacetylbaccatin III Usage


Usage

10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties.

10-DAB (10-Deacetylbaccatin) can be gained from the le

Usage10-Deacetyl Baccatin III is an impurity of Paclitaxel (P132500) and derivatives.
UsageA intermediate in the synthesis of Taxol and derivatives

Biological Activity


10-deacetylbaccatin III is an intermediate in the biosynthetic pathway of the taxane, paclitaxel. Taxanes disrupt mitosis by preventing microtubule destabilization and spindle fiber formation in animal cells (Molè-Bajer, 1983). As a consequence of this mechanism, yew trees are slow growing organisms. Without mitosis, cells, especially cells with a high replication rate such as tumor cells, cannot divide. Taxanes are currently being investigated as possible treatment for certain cancers, and paclitaxel, is currently approved by the FDA for treatment of AIDS-related Karposi sarcoma, breast cancer, non-small cell lung cancer, and ovarian cancer.



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