Benzocaine Hydrochloride / Benzocaine Base Topical Anesthetic Drugs
ORTHESIN; Ora-jel; ethyl 4-aminobenzene carboxylate; Euphagin;
4-ethoxycarbonylaniline; AETHOFORM; Norcaine; ethyl ester of
p-aminobenzoic acid; 4-amino-benzoic acid ethyl ester; Norcain;
Benzocaine; Ethoform; Topcaine; Anaesthin; Benzoic acid, 4-amino-,
ethyl ester; Solu H; ethyl 4-amino-benzoate; p-aminobenzoic acid
Appearance : White crystalline powder
Melting Point: 89-92ºC
Boiling Point: 172ºC (17 torr)
Flash Point: > 110ºC
Refractive Index: 1.5502
Stability: Stable. Combustible. Incompatible with strong oxidizing
Storage Condition: 0-6ºC
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Benzocaine is a fat soluble surface anaesthetic. Compared with
several other local anesthetics such as lidocaine, tetracaine,
etc., the strength of effect is small. Owing to its playing role in
mucosal, people feel comfort. It is a fat soluble and strong drug,
therefore it is easy to combine with the lipid layer of the mucosa
or skin, but not easily go through the human body to produce toxic.
Benzocaine is a local anesthetic (numbing medication). It works by
blocking nerve signals in your body.
Benzocaine topical is used to reduce pain or discomfort caused by
minor skin irritations, sore throat, sunburn, teething pain,
vaginal or rectal irritation, ingrown toenails, hemorrhoids, and
many other sources of minor pain on a surface of the body.
Benzocaine is also used to numb the skin or surfaces inside the
mouth, nose, throat, vagina, or rectum to lessen the pain of
inserting a medical instrument such as a tube or speculum.
Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). It can
be prepared from PABA and ethanol by Fischer esterification or via
the reduction of ethyl p-nitrobenzoate. Benzocaine is sparingly
soluble in water; it is more soluble in dilute acids and very
soluble in ethanol, chloroform and ethyl ether. The melting point
of benzocaine is 88-90 °C, and the boiling point is about 310 °C.
The density of benzocaine is 1.17 g/cm3.
Benzocaine is used to relieve pain and itching caused by conditions
such as sunburn or other minor burns, insect bites or stings,
poison ivy, poison oak, poison sumac, minor cuts, or
scratches.Benzocaine belongs to a group of medicines known as
topical local anesthetics. It deadens the nerve endings in
the skin. This medicine does not cause unconsciousness like general
anesthetics do when used for surgery.
Benzocaine Side Effects
Side effects that you should report to your doctor or health care
professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of
the face, lips, or tongue
- breathing problems
- dizziness or drowsiness
- fast or slow heartbeat
- increased sweating
- restlessness, nervousness, anxiety