API Fluorocytosine Drug 2022-85-7 for toxic antifungal Pyridines
4-Amino-5-fluoro-2(1H)-pyrimidinone; 5-Fluorocytosine; Alcobon;
|Appearance||White crystalline powder|
Jusheng Packing: 1)Aluminum Foil Bag: 100g, 500g, 1Kg 2)Fiber Drum:
Jusheng Delivery Method: HKEMS, DHL, TNT, UPS, FEDEX, EMS, China
Air Post etc.
Jusheng Clearance Rate: 100% Custom Pass, Diguised Package and Safe
Jusheng Delivery Time: 5-14 Working Days, Tracking Number Available
Jusheng Payment Terms: T/T, MoneyGram, Western Union and Bitcoin
Jusheng Origin: Hubei Province, China
Jusheng Brand Name: Jusheng Brand
Jusheng Production Capacity: 1000Kg/Month
Flucytosine, or 5-fluorocytosine, a fluorinated pyrimidine
analogue, is a synthetic antimycotic drug.
It is structurally related to the cytostatic fluorouracil and to
floxuridine. It is available in oral and in some countries also in
injectable form. A common brand name is Ancobon. Flucytosine was
first synthesized in 1957 but its antifungal properties were
discovered in 1964. The drug is dispensed in capsules of 250 mg and
500 mg strength. The injectable form is diluted in 250 mL saline
solution to contain 2.5 g total (10 mg/mL). The solution is
physically incompatible with other drugs including amphotericin B.
It is on the World Health Organization's List of Essential
Medicines, the most important medication needed in a basic health
Medical Application API Fluorocytosine:
1. Flucytosine by mouth is used for the treatment of serious
infections caused by susceptible strains of Candida orCryptococcus
neoformans. It can also be used for the treatment of chromomycosis
(chromoblastomycosis), if susceptible strains cause the infection.
2. Flucytosine must not be used as a sole agent in life-threatening
fungal infections due to relatively weak antifungal effects and
fast development of resistance, but rather in combination with
amphotericin B and/or azole antifungals such as fluconazole or
itraconazole. Minor infections such as candidal cystitis may be
treated with flucytosine alone. In some countries, treatment with
slow intravenous infusions for no more than a week is also a
therapeutic option, particular if the disease is life-threatening.
3. Serious fungal infections may occur in those who are
immunocompromised. These people benefit from combination therapy
including flucytosine, but the incidence of side-effects of a
combination therapy, particular with amphotericin B, may be higher.