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Oral Corticosteroids Betamethasone

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City: Wuhan
Province/State: Hubei
Country/Region: China
Tel: 0086-27-59599243
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Oral Corticosteroids Betamethasone

Brand Name : Jusheng Brand
Model Number : 378-44-9
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10grams
Price : Discount is possible if your order is big enough
Payment Terms : T/T, Western Union, MoneyGram, L/C, Bitcion, Paypal
Supply Ability : 1000kg/month
Delivery Time : within 2 working days
Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
CAS : 378-44-9
MF : C22H29FO5
Apparence : Almost White Powder
Purity : 99%
Usage : Anti - Inflammatory Medicine
Other Name : Celestene;Prestwick_703
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Oral Corticosteroids Betamethasone 378-44-9 Anti - Inflammatory Medicine Powder


Quick detail


Name:Betamethasone
CAS No.:378-44-9
Formula:C22H29FO5
Molecular Weight:434.50
Synonyms:Celestene;Prestwick_703;9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;Rinderon A;Cidoten;beta-Methasone alcohol;Betamethazone;Bedifos; Prednisolone, 9-fluoro-16beta-methyl-;Betamamallet;Betamethasone (JP14/USP);9-alpha-Fluoro-16-beta-methylprednisolone;Betafluorene;9-Fluoro-11-beta,17,21-trihydroxy-16-beta-methylpregna-1,4-diene-3,20-dione; Betapredol;Visubeta;
EINECS:206-825-4
Density:1.32 g/cm3
Melting Point:235-237 °C
Boiling Point:568.2 °C at 760 mmHg
Flash Point:297.5 °C
Appearance:white to off-white solid

Introduction of Betamethasone


Betamethasone, belongs to adrenal corticosteroids, it is a isomer of dexamethasone , and the role of betamethasone is similiar to prednisolone and dexamethasone , it has anti-inflammatory, anti-rheumatic, anti-allergic and suppression of the immune and other pharmacological effects, its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone etc. ,


Betamethasone sodium retention effect is a hundred times more than hydrocortisone, in primary adrenal hypofunction, it can be used together with glucocorticoid for replacement therapy ,and it is used for preventing or inhibiting cell-mediated immune response, delaying allergic reactions and reducing the primary immune response expansion ,it is used for low renin and low aldosterone syndrome and autonomic neuropathy induced orthostatic hypotension.


Currently betamethasone is also used for the treatment of active rheumatoid arthritis, rheumatoid arthritis, lupus, severe bronchial asthma, severe dermatitis, acute leukemia, atopic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, and pruritus and comprehensive treatment of certain infections.


Betamethasone Usage:


  1. Hormone drugs.
  2. It is mainly used for anti-inflammatory and anti-allergic.
  3. It is suitable for rheumatoid arthritis and various skin diseases.
  4. Betamethasone role is similiar to dexamethasone,
  5. its anti-inflammatory effect is stronger than dexamethasone, triamcinolone, hydrocortisone and it has few side effects.

Technical Test Sheet (TTS) of Glucocorticoid Steroids Betamethasone


Identification (B,C)Complies with the StandardComplies
Specific optical Rotation+118°~+126°+123.5°
Single impurityNot more than 1.0%0.29%
impurity that ≥0.5%Not more than oneComplies
total impuritiesNot more than 2.0%0.64%
Loss on dryingNot more than 1.0%0.05%
Assay(UV, basis on drying)97.0%~103.0%98.8%
MethanolNot more than 3000ppmComplies
Ethyl acetateNot more than 5000ppmComplies
AcetoneNot more than 5000ppmComplies
DMFNot more than 880ppmComplies
DichloromethaneNot more than 600ppmComplies
ChloroformNot more than 60ppmComplies
Particle Size100.0%<30umComplies
Residue on ignitionNot more than 0.2%0.03%
ConclusionQualified


Product Tags:

anti inflammatory medications

      

anti histaminic drugs

      
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