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98% Purity Brain Enhancing Drugs Powder Donepezil HCl CAS 120011-70-3

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98% Purity Brain Enhancing Drugs Powder Donepezil HCl CAS 120011-70-3

Brand Name : Jusheng Brand
Model Number : 120011-70-3
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10grams
Price : Discount is possible if your order is big enough
Payment Terms : T/T, Western Union, MoneyGram, L/C, Bitcion, Paypal
Supply Ability : 1000kg/month
Delivery Time : within 2 working days
Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
CAS : 120011-70-3
Other name : Donepezil HCl, ARICEPT
Apparence : Almost White Crystalline Powder
Purity : More Than 98%
MOQ : 10grams
Packing : As Your Requirement
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Medical Aricept Donepezil HCl CAS 120011-70-3 Improves Brain Function Drugs

Nootropic Supplements product list.pdf

Quick detail


Product Name:Donepezil HCl
Synonyms:1h-inden-1-one,2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)me;bnag;e2020(pharmaceutical);AKOS 226-31;ARICEPT;DONEPEZIL HCL;DONEPEZIL HYDROCHLORIDE;E-2020
CAS:120011-70-3
MF:C24H30ClNO3
MW:415.95
Product Categories:Active Pharmaceutical Ingredients;Nootropic;Intermediates & Fine Chemicals;Pharmaceuticals;Donepezil;Aromatics;Heterocycles;Inhibitors;Isotope Labelled Compounds;Other APIs;Antipsychotic


Usage


UsageA nootropic. An inhibitor of acetylcholinesterase
UsageA labelled nootropic. An inhibitor of acetylcholinesterase.
UsageAntialzheimer
UsageLabeled Donepezil, intended for use as an internal standard for the quantification of Donepezilby GC- or LC-mass spectrometry.
Definition

ChEBI: Donepezil hydrochloride is a centrally acting reversible acetyl cholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's
disease where it is used to increase cortical acetylcholine.


Donepezil HCl ​ Introduction


ARICEPT (donepezil hydrochloride) is a reversible inhibitor of the enzyme acetylcholinesterase, known chemically as (±)-2, 3-dihydro-5, 6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1Hinden- 1-one hydrochloride. Donepezil hydrochloride is commonly referred to in the pharmacological literature as E2020. It has an empirical formula of C24H29NO3HCl and a molecular weight of 415.96. Donepezil hydrochloride is a white crystalline powder and is freely soluble in chloroform, soluble in water and in glacial acetic acid, slightly soluble in ethanol and in acetonitrile, and practically insoluble in ethyl acetate and in n-hexane.

Inactive ingredients in 5 mg and 10 mg tablets are lactose monohydrate, corn starch, microcrystalline cellulose, hydroxypropyl cellulose, and magnesium stearate. The film coating contains talc, polyethylene glycol, hypromellose, and titanium dioxide. Additionally, the 10 mg tablet contains yellow iron oxide (synthetic) as a coloring agent.
Inactive ingredients in 23 mg tablets include ethylcellulose, hydroxypropyl cellulose, lactose monohydrate, magnesium stearate, and methacrylic acid copolymer, Type C. The film coating includes ferric oxide, hypromellose 2910, polyethylene glycol 8000, talc, and titanium dioxide.

Donepezil HCl INDICATIONS


Sections or subsections omitted from the full prescribing information are not listed. ARICEPT is indicated for the treatment of dementia of the Alzheimer’s type. Efficacy has been demonstrated in patients with mild, moderate, and severe Alzheimer’s disease.

DOSAGE AND ADMINISTRATION


  1. Dosing In Mild To Moderate Alzheimer’s Disease

The recommended starting dosage of ARICEPT is 5 mg administered once per day in the evening, just prior to retiring. The maximum recommended dosage of ARICEPT in patients with mild to moderate Alzheimer’s disease is 10 mg per day. A dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks.

2. Dosing In Moderate To Severe Alzheimer’s Disease

The recommended starting dosage of ARICEPT is 5 mg administered once per day in the evening, just prior to retiring. The maximum recommended dosage of ARICEPT in patients with moderate to severe Alzheimer’s disease is 23 mg per day. A dose of 10 mg should not be administered until patients have been on a daily dose of 5 mg for 4 to 6 weeks. A dose of 23 mg per day should not be administered until patients have been on a daily dose of 10 mg for at least 3 months.

Warnings
  • KEEP OUT OF REACH OF CHILDREN
  • DO NOT EXCEED RECOMMENDED DOSE
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.


What are the possible side effects of donepezil (Aricept, Aricept ODT)?


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using donepezil and call your doctor at once if you have any of these serious side effects:

  • black, bloody, or tarry stools;
  • coughing up blood or vomit that looks like blood or coffee grounds;
  • painful or difficult urination;
  • seizure (black-out or convulsions);

Less serious side effects may include:

  • nausea, vomiting, diarrhea;
  • loss of...


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