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Sildenafil (Viagra) Male Enhancement Drugs Powder CAS 139755-83-2 Hormone

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Sildenafil (Viagra) Male Enhancement Drugs Powder CAS 139755-83-2 Hormone

Brand Name : Jusheng Brand
Model Number : 139755-83-2
Certification : ISO, 9001, USP
Place of Origin : China
MOQ : 10grams
Price : Discount is possible if your order is big enough
Payment Terms : T/T, Western Union, MoneyGram, L/C,
Supply Ability : 1000kg/month
Delivery Time : within 2 working days
Packaging Details : 10g, 20g, 50g , 100g, 500g. 1kg, 10kg
CAS : 171596-29-5
Alias : Sildenafil , Viagra
Apparence : Almost White Crystalline Powder
Purity : 99%
Fuction : Men Sex Steroid Hormone
Stock : Enough Stock
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Sildenafil (Viagra) Male Enhancement Drugs Powder CAS 139755-83-2 Hormone

Quick detail


Sildenafil (Viagra)
Synonyms: sildenafil citrate; viagra
CAS No.: 139755-83-2
Assay: 98%-101%
Appearance: white powder
Packing: 1kg/foil bag


Description


Sildenafil (Viagra) is used to treat erectile dysfunction (impotence; inability to get or keep an erection) in men. Sildenafil (Revatio) is used to improve the ability to exercise in adults with pulmonary arterial hypertension (PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness). Children should not usually take sildenafil, but in some cases, a doctor may decide that sildenafil (Revatio) is the best medication to treat a child's condition. Sildenafil is in a class of medications called phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.

Application:


Viagra (Sildenafil citrate) is a drug used to treat erectile dysfunction (impotence) in males and pulmonary arterial hypertension (PAH).
2. Sildenafil citrate is the raw material of Viagra.
3. Viagra is a kind of male sex enhancer drug.
4. Viagra is the first drug patented for use of erectile dysfunction.
5. Viagra treats erectile dys function and works by relaxing muscles and increases blood flow to particular areas of the body .
6. Its effects last up to four hours.

In 16 separate 4-24 week trials of men (over 18 years old) who suffered from impotence for longer than 6 months, dosages between 10-200 mgs were administered. Significant improvements in erectile function, including frequency of penetration as well as erection duration post penetration, were reported with Sildenfil treatment compared to the placebo group.
Erections were improved in 72% of the Viagra group verses 18% of the placebo group. In all cases effects were dependant upon dosage and improvement was the greatest when dosage exceeded 100 mgs. Responses were decreased by 40-60% in patients suffering from diabetes and prostatectomy, respectively. Withdrawal rates were less than 5% related to negative side effects and limited response rates.

Sex hormone effects


Estrogens have a variety of effects on both the sexual organs and diverse target tissues. Although they play different roles in normal male and female physiology, they do in some cases have analogous activities in both sexes.

EffectMenWomen
Female sexual characteristics:estrogens promote the development of breast tissue and the growth and differentiation of the sexual organs.Men with liver disease who have an excess of estrogen because of the inability of their liver to metabolize it develop gynecomastia, palmar erythema, and spider angiomas.Estrogen expression is responsible for female primary and secondary sexual characteristics. Estradiol promotes epithelial cell proliferation in the uterine endometrium and mammary glands of the breasts. In the absence of progesterone, endometrial thickening will proceed unopposed, potentially leading to endometrial hyperplasia and cancer. High exposure to estadiol has also been shown to increase risk for certain breast cancers.
Energy homeostasis and metabolism: estrogen deficiency can result in development of the metabolic syndrome.In men, aromatase deficiency has been associated with the development of metabolic derangement characterized by increased circulating LDL, decreased glucose tolerance, hyperinsulinemia, and hepatic steatosis.In women, estrogen deficiency has been associated with an increase in adipose cell volume and the growth of peripheral fat pads.

Prevention of bone loss:estrogens act on osteoblasts and osteoclasts to decrease resorption of bone through:
(1) increasing expression of factors on osteoblasts which promote osteoclast apoptosis;
(2) increasing osteoprotegrin expression and decreasing RANK-RANK ligand signalling

Men with estrogen insensitivity or aromatase deficiency are at increased risk of loss in bone density and osteoporosis.Menopause is thought to cause an increase risk of osteoporosis.


Vasoprotection: estrogens may decrease the risk of atherogenesis in males and females.

Case studies have demonstrated premature atherogenesis in aromatase-deficient men.Animal studies have demonstrated a role for estrogen in preventing the formation of new atherosclerotic plaques, but this role has not yet been demonstrated in humans.


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